By A. N. Paruta, R. Piekos

Certainly one of 3 volumes which jointly hide all stated solubility facts for a big pharmaceutical classification: the sulfonamides. a data of solubility information is precious in all pharmaceutical learn. released solubility facts for the name compounds were compiled and severely evaluated, leading to urged solubility values which practicing scientists might use with self belief. every one quantity comprises structural formulae and molecular weight information for the compounds coated, with ease grouped jointly

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Extra resources for 4–Aminobenzenesulfonamides. 6-Membered Heterocyclic Substituents and Miscellaneous Systems

Sample text

Schweiz. Med. 73(13), 403-8. Wochenschr. PREPARED BY: R. 8 3 a C a l c u l a t e d by compiler AUXILIARY METHOD/APPARATUS/PROCEDURE : Nothing specified. INFORMATION SOURCE A N D PURITY OF MATERIALS: Nothing specified. ESTIMATED ERROR: Nothing specified.

8 χ 10~ 3 _3 mol dm , compiler ) . AUXILIARY INFORMATION METHOD /APPARATUS /PROCEDURE : SOURCE AND PURITY OF MATERIALS: A mixt of sulfapyridine and water was Source and purity of sulfapyridine were agitated for 24 hours at 37°C. not specified. Distilled water was used. ESTIMATED ERROR: Nothing specified REFERENCES: 25 iD R I G I N A L M E A S U R E M E N T S : COMPONENTS : (1) Benzenesulfonamide, pyridinylC (2) H N 11 11 3°2 Water; Tréfouël, M. 4-amino-N-2- Bull. (sulfapyridine); S; H 20 ; Acad.

The bubbling a stream of acetone-satd N, fitra- absence of impurities and water was confirm- tion, and distn off the solvent without con ed by procedures of the German Pharmacopeia tact with air. VI and Spanish Pharmacopeia VIII. Two exhangeab1e disso1n vessels of 15 and 8 cm 3 working capacity The purity of the solute was not specified. were used depending on the soly of solute. The app was immersed in a thermostat. The vo1s of acetone used were 15 or 5 cm 3 , and ESTIMATED ERROR: Soly: measurements were repeated until 2 values not differing in the second satd solns were filtered, weighed, the soldecimal were obtained (author).

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